Searchable abstracts of presentations at key conferences on calcified tissues

ba0007p16 | (1) | ICCBH2019

Higher neonatal bone mineral content and lower IL-6 levels in offspring of overweight/obese women following antenatal exercise: The IMPROVE randomized controlled trial (RCT)

Seneviratne SN , Derraik JGB , Jiang Yannan , Gusso Silmara , Rodrigues RO , Peres Geovana , Biggs Janene , Craigie Susan , McCowan Lesley , Parry Graham , Ekeroma Alec , Cutfield WS , Hofman PL

Objectives: The in-utero environment affects fetal development and health and disease risk in adulthood1. Maternal obesity during pregnancy is associated with low-grade inflammation and long-term offspring health risks2. Pro-inflammatory adipocytokines (TNF-α/IL-6) are linked with later obesity, insulin resistance and osteoporosis3 4, while low early-life bone mineral content (BMC) is associated with osteoporosis5. We assessed the impact o...